Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence

Nov 27, 2023

Publications

Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence

Publication: mBio
Authors: Sunita Gulati, Andreas Holm Mattsson, Sophie Schussek, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Lisa A. Lewis, Peter A. Rice, Pär Comstedt, Sanjay Ram

Targeting neoantigens to APC- surface molecules improves the immunogenicity and anti-tumor efficacy of a DNA cancer vaccine

Aug 29, 2023

Publications

Targeting neoantigens to APC- surface molecules improves the immunogenicity and anti-tumor efficacy of a DNA cancer vaccine

Publication: Frontier in Immunology 
Authors: Marina Barrio-Calvo, Søren Vester Kofoed, Sofie Cens Holste, Anders Bundgård Sørensen, Nadia Viborg, Jens Vindahl Kringelum, Daniela Kleine-Kohlbrecher, Christian Skjødt Steenmans, Christian Bahne Thygesen, Birgitte Rønø and Stine Friis

DNA immunization with in silico predicted T-cell epitopes protects against lethal SARS-CoV-2 infection in K18-hACE2 mice

Jul 11, 2023

Publications

DNA immunization with in silico predicted T-cell epitopes protects against lethal SARS-CoV-2 infection in K18-hACE2 mice

Publication: Frontiers
Authors: Gry Persson, Katherine H. Restori, Julie Hincheli Emdrup, Sophie Schussek, Michael Schantz Klausen, McKayla J. Nicol, Bhuvana Katkere, Birgitte Rønø, Girish Kirimanjeswara & Anders Bundgaard Sørensen

 

Using AI to create a vaccine revolution

Jun 1, 2023

Publications

Using AI to create a vaccine revolution

Publication: Biopharma Dealmakers
Authors: Evaxion & Nature Research Custom Media

DNA based neoepitope vaccination induces tumor control in syngeneic mouse models

May 27, 2023

Publications

DNA based neoepitope vaccination induces tumor control in syngeneic mouse models

Publication: npj Vaccines
Authors: Nadia Viborg, Michail Angelos Pavlidis, Marina Barrio-Calvo, Stine Friis, Thomas Trolle, Anders Bundgaard Sørensen, Christian Bahne Thygesen, Søren Vester Kofoed, Daniela Kleine-Kohlbrecher, Sine Reker Hadrup & Birgitte Rønø

Endogenous viral elements constitute a complementary source of antigens for personalized cancer immunotherapy

Mar 27, 2023

Publications

Endogenous viral elements constitute a complementary source of antigens for personalized cancer immunotherapy

Publication: bioRxiv
Authors: Christian Garde, Michail A Pavlidis, Pablo Garces, Emma J Lange, Sri H Ramarathinam, Mateo Sokac, Kirti Pandey, Pouya Faridi, Johanne Ahrenfeldt, Shanzou Chung, Stine Friis, Daniela Kleine-Kohlbrecher, Nicolai J Birkbak, Jens V Kringelum, Birgitte Rono, Anthony W Purcell, Thomas Trolle

Benchmarking freely available HLA typing algorithms across varying genes, coverages and typing resolutions

Nov 16, 2022

Publications

Benchmarking freely available HLA typing algorithms across varying genes, coverages and typing resolutions

Publication: Frontiers in Immunology
Authors: Nikolas Hallberg Thuesen, Michael Schantz Klausen, Shyam Gopalakrishnan, Thomas Trolle and Gabriel Renaud

Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma

Jan 10, 2022

Publications

Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma

Publication: OncoImmunology
Authors: Sofie Kirial Mørk, Mohammad Kadivar, Kalijn Fredrike Bol, Arianna Draghi, Marie Christine Wulff Westergaard, Signe Koggersbøl Skadborg, Nana Overgaard, Anders Bundgård Sørensen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Christina Westmose Yde, Thomas Trolle, Christian Garde, Jens Friis-Nielsen, Nis Nørgaard, Dennis Christensen, Jens Vindahl Kringelum, Marco Donia, Sine Reker Hadrup & Inge Marie Svane

Efficient Generative Modelling of Protein Structure Fragments using a Deep Markov Model

Jun 22, 2021

Publications

Efficient Generative Modelling of Protein Structure Fragments using a Deep Markov Model

Publication: bioRxiv
Authors: Christian B Thygesen, Christian Skjødt Steenmans, Ahmad Salim Al-Sibahi, Lys Sanz Moreta, Anders Bundgård Sørensen, Thomas Hamelryck